Publications

Patients with chronic prostatitis/chronic pelvic pain syndrome show T helper type 1 (Th1) and Th17 self-reactive immune responses specific to prostate and seminal antigens and diminished semen quality

Motrich, R. D., Breser, M. L., Molina, R. I., Tissera, A., Olmedo, J. J., & Rivero, V. E. (2020). BJU international, 10.1111/bju.15117. Advance online publication.

https://doi.org/10.1111/bju.15117

 

Differences in T regulatory cells between mouse strains frequently used in immunological research: Treg cell quantities and subpopulations in NOD, B6 and BALB/c mice.

Godoy, G. J., Paira, D. A., Olivera, C., Breser, M. L., Sanchez, L. R., Motrich, R. D., & Rivero, V. E. (2020). Immunology letters, 223, 17–25. https://doi.org/10.1016/j.imlet.2020.04.006

 

T Regulatory Cells From Non-obese Diabetic Mice Show Low Responsiveness to IL-2 Stimulation and Exhibit Differential Expression of Anergy-Related and Ubiquitination Factors.

Godoy, G. J., Olivera, C., Paira, D. A., Salazar, F. C., Ana, Y., Stempin, C. C., Motrich, R. D., & Rivero, V. E. (2019). Frontiers in immunology, 10, 2665. https://doi.org/10.3389/fimmu.2019.02665

 

 IL-10 Producing B Cells Dampen Protective T Cell Response and Allow Chlamydia muridarum Infection of the Male Genital Tract.

Sanchez, L. R., Godoy, G. J., Gorosito Serrán, M., Breser, M. L., Fiocca Vernengo, F., Engel, P., Motrich, R. D., Gruppi, A., & Rivero, V. E. (2019). Frontiers in immunology, 10, 356. https://doi.org/10.3389/fimmu.2019.00356

 

A Plasmonic Approach to Study Protein Interaction Kinetics through the Dimerization of Functionalized Ag Nanoparticles.

Mercadal, P. A., Motrich, R. D., & Coronado, E. A. (2019). Scientific reports, 9(1), 13122. https://doi.org/10.1038/s41598-019-49583-2

 

Implications of prostate inflammation on male fertility.

Motrich, R. D., Salazar, F. C., Breser, M. L., Mackern-Oberti, J. P., Godoy, G. J., Olivera, C., Paira, D. A., & Rivero, V. E. (2018). Andrologia, 50(11), e13093. https://doi.org/10.1111/and.13093

 

Chlamydia trachomatis neither exerts deleterious effects on spermatozoa nor impairs male fertility.

Puerta Suarez, J., Sanchez, L. R., Salazar, F. C., Saka, H. A., Molina, R., Tissera, A., Rivero, V. E., Cardona Maya, W. D., & Motrich, R. D. (2017). Scientific reports, 7(1), 1126. https://doi.org/10.1038/s41598-017-01262-w

 

Immunological Mechanisms Underlying Chronic Pelvic Pain and Prostate Inflammation in Chronic Pelvic Pain Syndrome.

Breser, M. L., Salazar, F. C., Rivero, V. E., & Motrich, R. D. (2017). Frontiers in immunology, 8, 898. https://doi.org/10.3389/fimmu.2017.00898

 

Male genital tract immune response against Chlamydia trachomatis infection.

Mackern-Oberti, J. P., Motrich, R. D., Damiani, M. T., Saka, H. A., Quintero, C. A., Sánchez, L. R., Moreno-Sosa, T., Olivera, C., Cuffini, C., & Rivero, V. E. (2017). Reproduction (Cambridge, England), 154(4), R99–R110. https://doi.org/10.1530/REP-16-0561.

 

Chronic Infection of the Prostate by Chlamydia muridarum Is Accompanied by Local Inflammation and Pelvic Pain Development.

Sanchez, L. R., Breser, M. L., Godoy, G. J., Salazar, F. C., Mackern-Oberti, J. P., Cuffini, C., Motrich, R. D., & Rivero, V. E. (2017). The Prostate, 77(5), 517–529. https://doi.org/10.1002/pros.23291

 

Chronic Pelvic Pain Development and Prostate Inflammation in Strains of Mice With Different Susceptibility to Experimental Autoimmune Prostatitis.

Breser, M. L., Motrich, R. D., Sanchez, L. R., & Rivero, V. E. (2017). The Prostate, 77(1), 94–104. https://doi.org/10.1002/pros.23252

 

Design of a novel plasmonic nanoconjugated analytical tool for ultrasensitive antigen quantification.

Fraire, J. C., Motrich, R. D., & Coronado, E. A. (2016). Nanoscale, 8(39), 17169–17180. https://doi.org/10.1039/c6nr04897h

 

Regulatory T cells control strain specific resistance to Experimental Autoimmune Prostatitis.

Breser, M. L., Lino, A. C., Motrich, R. D., Godoy, G. J., Demengeot, J., & Rivero, V. E. (2016). Scientific reports, 6, 33097. https://doi.org/10.1038/srep33097

 

IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome.

Motrich, R. D., Breser, M. L., Sánchez, L. R., Godoy, G. J., Prinz, I., & Rivero, V. E. (2016). Pain, 157(3), 585–597. https://doi.org/10.1097/j.pain.0000000000000405

 

Transglutaminase 4 as a prostate autoantigen in male subfertility.

Landegren, N., Sharon, D., Shum, A. K., Khan, I. S., Fasano, K. J., Hallgren, Å., Kampf, C., Freyhult, E., Ardesjö-Lundgren, B., Alimohammadi, M., Rathsman, S., Ludvigsson, J. F., Lundh, D., Motrich, R., Rivero, V., Fong, L., Giwercman, A., Gustafsson, J., Perheentupa, J., Husebye, E. S., … Kämpe, O. (2015). Science translational medicine, 7(292), 292ra101. https://doi.org/10.1126/scitranslmed.aaa9186

 

Chlamydia trachomatis infection of the male genital tract: an update.

Mackern-Oberti, J. P., Motrich, R. D., Breser, M. L., Sánchez, L. R., Cuffini, C., & Rivero, V. E. (2013). Journal of reproductive immunology, 100(1), 37–53. https://doi.org/10.1016/j.jri.2013.05.002

 

Expression of CXCR3 on specific T cells is essential for homing to the prostate gland in an experimental model of chronic prostatitis/chronic pelvic pain syndrome.

Breser, M. L., Motrich, R. D., Sanchez, L. R., Mackern-Oberti, J. P., & Rivero, V. E. (2013). Journal of immunology (Baltimore, Md. : 1950), 190(7), 3121–3133. https://doi.org/10.4049/jimmunol.1202482

 

Old players with a newly defined function: Fra-1 and c-Fos support growth of human malignant breast tumors by activating membrane biogenesis at the cytoplasm.

Motrich, R. D., Castro, G. M., & Caputto, B. L. (2013). PloS one, 8(1), e53211. https://doi.org/10.1371/journal.pone.0053211

 

Male rat genital tract infection with Chlamydia muridarum has no significant consequence on male fertility.

Motrich, R. D., Sanchez, L., Maccioni, M., Mackern-Oberti, J. P., & Rivero, V. E. (2012). The Journal of urology, 187(5), 1911–1917. https://doi.org/10.1016/j.juro.2011.12.055

 

Male rodent genital tract infection with Chlamydia muridarum: persistence in the prostate gland that triggers self-immune reactions in genetically susceptible hosts.

Mackern-Oberti, J. P., Motrich, R. D., Breser, M. L., Cejas, H., Cuffini, C., Maccioni, M., & Rivero, V. E. (2011). The Journal of urology, 186(3), 1100–1106. https://doi.org/10.1016/j.juro.2011.04.086

 

Innate immunity in the male genital tract: Chlamydia trachomatis induces keratinocyte-derived chemokine production in prostate, seminal vesicle and epididymis/vas deferens primary cultures.

Mackern-Oberti, J. P., Maccioni, M., Breser, M. L., Eley, A., Miethke, T., & Rivero, V. E. (2011). Journal of medical microbiology, 60(Pt 3), 307–316. https://doi.org/10.1099/jmm.0.024877-0

 

Chemokine response induced by Chlamydia trachomatis in prostate derived CD45+ and CD45- cells.

Mackern Oberti, J. P., Breser, M. L., Nuñez, N., Maccioni, M., Rodríguez, N., Wantia, N., Ertl, T., Miethke, T., & Rivero, V. E. (2011). Reproduction (Cambridge, England), 142(3), 427–437. https://doi.org/10.1530/REP-11-0163

 

Crucial role of interferon-gamma in experimental autoimmune prostatitis.

Motrich, R. D., van Etten, E., Baeke, F., Riera, C. M., Mathieu, C., & Rivero, V. E. (2010). The Journal of urology, 183(3), 1213–1220. https://doi.org/10.1016/j.juro.2009.11.008

 

Immunological Aspects of the Prostate Gland and Related Diseases

Mariana Maccioni, Virginia Elena Rivero, Ruben Dario Motrich, Gerardo Gatti, Juan Pablo Mackern Oberti, Virginia Andreani and Clelia Maria Riera*, . Current Immunology Reviews (2010) 6: 287. https://doi.org/10.2174/1573395511006040287

 

Effects of autoimmunity to the prostate on the fertility of the male rat.

Motrich, R. D., Mackern-Oberti, J. P., Maccioni, M., & Rivero, V. E. (2009). Fertility and sterility, 91(5 Suppl), 2273–2280. https://doi.org/10.1016/j.fertnstert.2008.06.046

 

Impact of vitamin D receptor activity on experimental autoimmune prostatitis.

Motrich, R. D., van Etten, E., Depovere, J., Riera, C. M., Rivero, V. E., & Mathieu, C. (2009). Journal of autoimmunity, 32(2), 140–148. https://doi.org/10.1016/j.jaut.2009.02.002

 

Autoimmune prostatitis: state of the art.

Motrich, R. D., Maccioni, M., Riera, C. M., & Rivero, V. E. (2007).Scandinavian journal of immunology, 66(2-3), 217–227. https://doi.org/10.1111/j.1365-3083.2007.01971.x

 

Autoimmune etiology in chronic prostatitis syndrome: an advance in the understanding of this pathology.

Rivero, V. E., Motrich, R. D., Maccioni, M., & Riera, C. M. (2007). Critical reviews in immunology, 27(1), 33–46. https://doi.org/10.1615/critrevimmunol.v27.i1.30

 

Chlamydia trachomatis occurrence and its impact on sperm quality in chronic prostatitis patients.

Motrich, R. D., Cuffini, C., Oberti, J. P., Maccioni, M., & Rivero, V. E. (2006). The Journal of infection, 53(3), 175–183. https://doi.org/10.1016/j.jinf.2005.11.007

 

Pathogenic consequences in semen quality of an autoimmune response against the prostate gland: from animal models to human disease.

Motrich, R. D., Maccioni, M., Ponce, A. A., Gatti, G. A., Oberti, J. P., & Rivero, V. E. (2006). Journal of immunology (Baltimore, Md. : 1950), 177(2), 957–967. https://doi.org/10.4049/jimmunol.177.2.957

 

Susceptibility of prostate epithelial cells to Chlamydia muridarum infection and their role in innate immunity by recruitment of intracellular Toll-like receptors 4 and 2 and MyD88 to the inclusion.

Mackern-Oberti, J. P., Maccioni, M., Cuffini, C., Gatti, G., & Rivero, V. E. (2006). Infection and immunity, 74(12), 6973–6981. https://doi.org/10.1128/IAI.00593-06

 

Presence of INFgamma-secreting lymphocytes specific to prostate antigens in a group of chronic prostatitis patients.

Motrich, R. D., Maccioni, M., Molina, R., Tissera, A., Olmedo, J., Riera, C. M., & Rivero, V. E. (2005). Clinical immunology (Orlando, Fla.), 116(2), 149–157. https://doi.org/10.1016/j.clim.2005.03.011

 

Reduced semen quality in chronic prostatitis patients that have cellular autoimmune response to prostate antigens.

Motrich, R. D., Maccioni, M., Molina, R., Tissera, A., Olmedo, J., Riera, C. M., & Rivero, V. E. (2005). Human reproduction (Oxford, England), 20(9), 2567–2572. https://doi.org/10.1093/humrep/dei073